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Transmembrane transport of polycyclic aromatic hydrocarbons by bacteria and functional regulation ofmembrane proteins

Hongqi Wang, Ruhan Jiang, Dekang Kong, Zili Liu, Xiaoxiong Wu, Jie Xu, Yi Li

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 1, doi: 10.1007/s11783-019-1188-2

Abstract: Analyze functional regulation of membrane proteins inthe transmembrane transport.This article explains the adsorption, uptake and transmembrane transport of PAHs by bacteria, the regulationof membrane protein function during the transmembrane transport.There are three different regulation mechanisms for uptake, depending on the state and size of the oilFinally, recognize the microscopic mechanism of PAHs biodegradation in terms of cell and membrane proteins

Keywords： Polycyclic aromatic hydrocarbons     Transmembrane transport     Adsorption and uptake of hydrocarbons     Proteomics     Functionalregulation of membrane protein     Single cell analysis technology    

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Effect of protein on PVDF ultrafiltration membrane fouling behavior under different pH conditions: interface

Xudong WANG,Miao ZHOU,Xiaorong MENG,Lei WANG,Danxi HUANG

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 4, doi: 10.1007/s11783-016-0855-9

Abstract: pH values of the BSA solution significantly impact the process of membrane fouling.Dramatic flux decline is caused by membrane–BSA adhesion force at start of filtration.XDLVO theory shows the polar or Lewis acid–base interaction plays a major role in membrane fouling.membrane–BSA, which illustrated that the more hydrophilic the membrane was, the better antifouling abilitymembrane fouling by changing the AB component of free energy.

Keywords： PVDF membrane     Membrane fouling     Adhesion force     Protein     Interfacial free energy    

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Mechanism of ethanol/water reverse separation through a functional graphene membrane: a molecular simulation

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 3,   Pages 347-357 doi: 10.1007/s11705-022-2246-z

Abstract: Graphene-based membranes with tunable apertures and functional groups have shown substantial potentialsimulations, for the first time, we reveal two-way selectivity in ethanol/water separation through functionalpreferred for hydroxylated graphene membranes because of the synergistic effects of molecular sieving and functional-groupA simulation of the operando condition shows that the PG membrane with an aperture size of 3.8 Å achieves

Keywords： reverse separation     graphene membrane     ethanol/water separation     molecular simulation    

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Charge and separation characteristics of nanofiltration membrane embracing dissociated functional groups

Zhun MA,Meng WANG,Xueli GAO,Congjie GAO

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 5,   Pages 650-658 doi: 10.1007/s11783-013-0605-1

Abstract: current work focused on the investigation of charge and separation characteristics of nanofiltration (NF) membraneembracing dissociated functional groups under different electrolyte solutions.The electro-kinetic method was carried out to assess the membrane volume charge density ( ) with differentThe results indicated that the dissociation of the hydrophilic functional groups and the specific adsorptioncontributed to charge formation on membrane surface.

Keywords： Sulfonated polyethersulfone nanofiltration membrane     charge characteristics     electro-kinetic method     volume    

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Construction and humoral immune response of Epstein-Barr virus latent membrane protein 2 DNA vaccine

Jianqing PAN PhD, Qin ZHANG MD, Daowen WANG MD, PhD,

Frontiers of Medicine 2009, Volume 3, Issue 4,   Pages 390-395 doi: 10.1007/s11684-009-0087-5

Abstract: We constructed a eukaryotic expression plasmid encoding Epstein-Barr virus latent membrane protein 2

Keywords： Epstein-Barr virus     latent membrane protein 2     nasopharyngeal carcinoma     humoral immunity    

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Topological reorganization and functional alteration of distinct genomic components in gallbladder cancer

Frontiers of Medicine doi: 10.1007/s11684-023-1008-8

Abstract: chromatin immunoprecipitation sequencing (ChIP-seq), we investigated structural reorganization and functionalCollectively, our data offer the landscape of hierarchical layers of cancer genome and functional alterations

Keywords： 3D genome     cancer     TADs     loop     gene regulation    

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Involvement of p38 mitogen-activated protein kinase in the regulation of platelet-derived growth factor

GONG Xiaowei, WEI Jie, LI Yusheng, CHENG Weiwei, DENG Peng, JIANG Yong

Frontiers of Medicine 2007, Volume 1, Issue 3,   Pages 248-252 doi: 10.1007/s11684-007-0047-x

Abstract: The aim of this study was to investigate the role of p38 mitogen-activated protein kinase (MAPK) in cell(MEFs) (〈0.001) as compared with the wild type cells (p38). p38 MAPK plays an important role in the regulation

Keywords： control     stimulation     mitogen-activated     growth factor     process    

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Regulation of radicals by hydrogen-donor solvent in direct coal liquefaction

Frontiers of Chemical Science and Engineering 2022, Volume 16, Issue 12,   Pages 1689-1699 doi: 10.1007/s11705-022-2186-7

Abstract: effects of different radicals on the cleavage of chemical bond were investigated employing density functional

Keywords： direct coal liquefaction     hydrogen-donor solvent     induced pyrolysis     radical mechanism     density functional    

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Effect of inhibiting tyrosine kinase Src expression on protein phosphatase 2A and tau phosphorylation

LIU Rong, ZENG Ji, ZHOU Xinwen, WANG Jianzhi, PEI Jinjing

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 235-238 doi: 10.1007/s11684-008-0044-8

Abstract: this study is to investigate the effect of tyrosine kinase Src on Tyrosine 307(Y307) phosphorylation, proteinsiRNA was transfected into cultured mouse neuroblastoma N2a cells to inhibit the expression of Src proteinTwelve hours after siRNA transfection, the protein level of Src was dramatically decreased, with decreasedHowever, the total PP2A protein level was also decreased, together with a decreased PP2A activity.Multiple factors may be involved in the cellular regulation of PP2A activity.

Keywords： hyperphosphorylation     PP2A activity     cellular regulation     siRNA     siRNA transfection    

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Regulation of NLR stability in plant immunity

Tao WANG, Jiaxin LI, Qian-Hua SHEN

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 2,   Pages 97-104 doi: 10.15302/J-FASE-2018248

Abstract: ubiquitination-26S proteasome system and the HSP90 chaperones have emerged as having key functions in the regulationThe N-end rule pathway of protein degradation is also directly linked to NLR stability.Recent progress in the regulation of NLR stability and turnover is summarized here, focusing on the key

Keywords： ubiquitin ligase     degradation     nucleotide-binding leucine-rich repeat receptor     plant immunity     proteasome     protein    

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Application of ultra-sonication, acid precipitation and membrane filtration for co-recovery of protein

Liangliang WEI,Kun WANG,Xiangjuan KONG,Guangyi LIU,Shuang CUI,Qingliang ZHAO,Fuyi CUI

Frontiers of Environmental Science & Engineering 2016, Volume 10, Issue 2,   Pages 327-335 doi: 10.1007/s11783-014-0763-9

Abstract: the processes of ultra-sonication and acid precipitation, and then the humic acid was recovered via membrane

Keywords： sewage sludge     co-recovery     proteins     humic acid     recycling     biodegradation rate    

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Antibody Therapies Targeting Complex Membrane Proteins Review

Georgina To´a Salazar, Ziyi Huang, Ningyan Zhang, Xue-Guang Zhang, Zhiqiang An,

Engineering 2021, Volume 7, Issue 11,   Pages 1541-1551 doi: 10.1016/j.eng.2020.11.013

Abstract:

In analyses of protein families that may serve as drug targets, membrane-associated G-protein-coupledHowever, various challenges put such membrane proteins among key groups of underutilized opportunitiesprotein, as well as adaptability through engineering into various antibody formats.However, the ease of raising and isolating specific, effective antibodies targeting membrane proteinsand discusses the preparation of membrane protein antigens and antibody generation, illustrated by select

Keywords： Antibody therapy     Complex membrane protein     Ion channels     Transporters     Membrane-bound enzymes     GPCRs    

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Moving policy and regulation forward for single-use plastic alternatives

Frontiers of Environmental Science & Engineering 2021, Volume 15, Issue 3, doi: 10.1007/s11783-021-1423-5

Abstract: Single-use plastics are often used once or cannot be reused for extended periods. They are widely consumed with the rapid development of social economy. The waste generated by single-use plastics threatens ecosystem health by entering the environment and ultimately restricts sustainable human development. The innovation of sustainable and environmentally friendly single-use plastic alternative materials and the joint participation of governments, enterprises and the public are promising technologies and management approaches that can solve the problem of single-use plastics wastes. The development of single-use plastic alternative products can be promoted fundamentally only by improving relevant legislation and standards, providing differentiated industrial policies, encouraging scientific and technological innovation and expanding public participation.

Keywords： Single-use plastic alternatives     Policy     Regulation     Sustainable development    

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Phase transition regulation and caloric effect

Frontiers in Energy 2023, Volume 17, Issue 4,   Pages 463-477 doi: 10.1007/s11708-023-0860-1

Abstract: Solid state refrigeration based on caloric effect is regarded as a potential candidate for replacing vapor-compression refrigeration. Numerous methods have been proposed to optimize the refrigeration properties of caloric materials, of which single field tuning as a relatively simple way has been systemically studied. However, single field tuning with few tunable parameters usually obtains an excellent performance in one specific aspect at the cost of worsening the performance in other aspects, like attaining a large caloric effect with narrowing the transition temperature range and introducing hysteresis. Because of the shortcomings of the caloric effect driven by a single field, multifield tuning on multicaloric materials that have a coupling between different ferro-orders came into view. This review mainly focuses on recent studies that apply this method to improve the cooling performance of materials, consisting of enlarging caloric effects, reducing hysteresis losses, adjusting transition temperatures, and widening transition temperature spans, which indicate that further progress can be made in the application of this method. Furthermore, research on the sign of lattice and spin contributions to the magnetocaloric effect found new phonon evolution mechanisms, calling for more attention on multicaloric effects. Other progress including improving cyclability of FeRh alloys by introducing second phases and realizing a large reversible barocaloric effect by hybridizing carbon chains and inorganic groups is described in brief.

Keywords： phase transition regulation     caloric effect     solid state refrigeration    

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The function and regulation of OTU deubiquitinases

Jiansen Du, Lin Fu, Yingli Sui, Lingqiang Zhang

Frontiers of Medicine 2020, Volume 14, Issue 5,   Pages 542-563 doi: 10.1007/s11684-019-0734-4

Abstract: character, structure and function of OTUs, such as the substrate specificity and catalytic activity regulation

Keywords： ubiquitin     OTU deubiquitinases     structure     function     regulation    

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Title Author Date Type Operation

Transmembrane transport of polycyclic aromatic hydrocarbons by bacteria and functional regulation ofmembrane proteins

Hongqi Wang, Ruhan Jiang, Dekang Kong, Zili Liu, Xiaoxiong Wu, Jie Xu, Yi Li

Journal Article

Effect of protein on PVDF ultrafiltration membrane fouling behavior under different pH conditions: interface

Xudong WANG,Miao ZHOU,Xiaorong MENG,Lei WANG,Danxi HUANG

Journal Article

Mechanism of ethanol/water reverse separation through a functional graphene membrane: a molecular simulation

Journal Article

Charge and separation characteristics of nanofiltration membrane embracing dissociated functional groups

Zhun MA,Meng WANG,Xueli GAO,Congjie GAO

Journal Article

Construction and humoral immune response of Epstein-Barr virus latent membrane protein 2 DNA vaccine

Jianqing PAN PhD, Qin ZHANG MD, Daowen WANG MD, PhD,

Journal Article

Topological reorganization and functional alteration of distinct genomic components in gallbladder cancer

Journal Article

Involvement of p38 mitogen-activated protein kinase in the regulation of platelet-derived growth factor

GONG Xiaowei, WEI Jie, LI Yusheng, CHENG Weiwei, DENG Peng, JIANG Yong

Journal Article

Regulation of radicals by hydrogen-donor solvent in direct coal liquefaction

Journal Article

Effect of inhibiting tyrosine kinase Src expression on protein phosphatase 2A and tau phosphorylation

LIU Rong, ZENG Ji, ZHOU Xinwen, WANG Jianzhi, PEI Jinjing

Journal Article

Regulation of NLR stability in plant immunity

Tao WANG, Jiaxin LI, Qian-Hua SHEN

Journal Article

Application of ultra-sonication, acid precipitation and membrane filtration for co-recovery of protein

Liangliang WEI,Kun WANG,Xiangjuan KONG,Guangyi LIU,Shuang CUI,Qingliang ZHAO,Fuyi CUI

Journal Article

Antibody Therapies Targeting Complex Membrane Proteins

Georgina To´a Salazar, Ziyi Huang, Ningyan Zhang, Xue-Guang Zhang, Zhiqiang An,

Journal Article

Moving policy and regulation forward for single-use plastic alternatives

Journal Article

Phase transition regulation and caloric effect

Journal Article

The function and regulation of OTU deubiquitinases

Jiansen Du, Lin Fu, Yingli Sui, Lingqiang Zhang

Journal Article